Stephen Fried is a native of Kansas City. He received two S.B. degrees (2009) from MIT in chemistry and physics and completed his doctoral training at Stanford under the mentorship of Prof. S. G. Boxer in 2014. He is currently a Junior Research Fellow of King’s College (University of Cambridge), researching chemical and synthetic biology at the MRC laboratory of molecular biology with Prof. J. W. Chin. Stephen’s graduate work focused on understanding the physical principles underpinning enzymes’ great catalytic power. His post-doctoral contributions include the co-invention of the stapled ribosome, the discovery of several new orthogonal tRNA-synthetase pairs for genetic code expansion, and the first systematic investigation of tRNA decoding in living cells.